Re: dissing omega 3

From: P Howgate (phowgate@clara.co.uk)
Date: Sat Apr 01 2006 - 04:57:46 PST

  • Next message: Pamela Tom: "Re: dissing omega 3 - correct web address for BMJ"

    Dear Liz, and others

    This story questioning benefits of omega-3 oils appeared in the UK media a
    few days ago, but didn't 'run'. Your links refer to 2 though separate
    topics, though there is a connection, and should be commented on separately.
    The first link, the British Medical Journal one, refers to an editorial in
    the journal which comments on a paper which questioned some claimed benefits
    the omega-3 oils and let me comment on that first.

    The paper is Hooper et al., 'Risks and benefits of omega 3 fats for
    mortality, cardiovascular disease, and cancer: systematic review'. It has
    not appeared in print yet, but a pdf file of it can be downloaded from
    http://bmj.bmijournals.com .Go to the site and enter hooper and omega 3 into
    the author and keywords boxes respectively in the top right and the paper
    and its link to the pdf file will be listed. It describes a meta-analysis of
    a large number of studies of the risks and benefits stated in the title.
    Their conclusion from this pooling and analysis of data was not the same as
    some previous meta-analyses, but those previous ones did not include the
    results of a recent large study. Let me quote the conclusion from the
    summary of the paper:"Long chain and shorter chain omega 3 fats do not have
    a clear effect on total mortality, combined cardiovascular events, or
    cancer." Within the paper is an highlighted box which I assume was inserted
    in the editorial process to catch the eye of the skimming reader. Here is
    what this box states under a subtitle 'What this study adds': "This
    systematic review assessed the health effects of long chain and shorter
    chain omega 3 fats (together or separately) on total mortality,
    cardiovascular events, cancer, and strokes in a wide group of participants
    and found no evidence of a clear benefit of omega 3 fats on health" Note
    that this editorial embellishment has changed the authors' '... do not have
    a clear effect on total mortality, combined cardiovascular events, or
    cancer.' to '...found no evidence of a clear benefit of omega 3 fats on
    health'. These 2 conclusions are not the same and that of the authors of the
    paper are more cautious and limited in scope than the editorial box suggest.
    The authors are quite explicit that they did not set out to examine claims
    for the health effects of omega-3 acids generally, but for some specific
    aspects of health, mortality, cardiovascular disease and cancer.

    It is a highly technical paper directed towards epidemiologists and can only
    be appreciated by specialists, but the reasonably informed person can follow
    the discussion. The authors discuss at some length the recent survey which
    swung their meta-analysis towards a no effect compared with previous
    analyses that did show an effect. The authors write in the section
    Interpretation: "It is not clear whether long chain or short chain omega 3
    fats (together or separately) reduce or increase total mortality,
    cardiovascular events, cancer, or strokes. Our findings do not rule out an
    important effect of omega 3 fats on total mortality, as robust trials at low
    risk of bias reported few deaths.". They also write: "UK guidelines
    encourage the general public to eat more oily fish, and higher amounts are
    advised after myocardial infarction (supported by trials after myocardial
    infarction). This advice should continue at present but the evidence should
    be reviewed regularly. It is probably not appropriate to recommend a high
    intake of omega 3 fats for people who have angina but have not had a
    myocardial infarction." These observations is not quite the clear-cut
    conclusions put out in the media in Britain.

    The first link in Liz's message is to an editorial in The BMJ of 24 March
    which is probably the source of the press release because the Hooper et al.
    is not yet published. Though called an Editorial it is more like a
    scientific paper rather than an editorial in a newspaper in that it cites
    references in a bibliography and is signed. After briefly summarising the
    conclusions of the Hooper et al paper it goes on to discuss health benefits
    of consumption of omega-3 oils other than on cardiovascular conditions. It
    is the last paragraph that to my mind is incorrect and contentious; I should
    quote it in full: "We are faced with a paradox. Health recommendations
    advise increased consumption of oily fish and fish oils, within limits, on
    the grounds that intake is generally low. However, industrial fishing has
    depleted the world's fish stocks by some 90% since 1950, and rising fish
    prices reduce affordability particularly for people with low incomes. Global
    production trends suggest that, although fish farming is expanding rapidly,
    we probably do not have a sustainable supply of long chain omega 3 fats.".
    For the claim that the world's fish stocks have been depleted by some 90%
    since 1950 the author cites a paper by Myers RA,& Worm B., 'Rapid worldwide
    depletion of predatory fish communities', Nature, 2003, 423:280-3. This
    paper is not available at the Nature site unless you have a subscription to
    the journal, but can be downloaded from the Berkley university site at
    http://seismo.berkeley.edu/~manga/eps3/myersandworm2003.pdf. This paper
    though is about depletion of stocks of predatory fish, not of stocks of fish
    generally. Predatory fish are not fished directly for fish meal and oil
    though both these products are obtained from wastes from processing of
    predatory fish, for example meal from fillet waste, oil from livers. Most
    fish oil is obtained from directed fisheries of pelagic fish. Over the last
    two decades or so the catch from industrialised fisheries has been around
    25-30 million tonnes/year other than in El NiZo years compared with about 4
    million tonnes of waste material going for reduction. FAO publishes on
    bi-annual basis a "The State of World Fisheries and Aquaculture" and as I
    read them they do not express great concern for the status of pelagic stocks
    caught for industrial purposes. It seems to me from my reading, though
    without specialised knowledge of the subject, that there is a sustainable
    supply of marine-sourced omega-3 fatty acids. What is up for discussion
    whether or not this sustainable production is adequate for all requirements,
    and how much is to be used in animal feeds and how much for human
    consumption.

    The author of the editorial has a point about affordability. In the UK
    anyway, fillets, skin-on, of predatory white-fleshed fish such as cod
    retails at around 20USD/kg, more expensive than chicken or of common cuts of
    pork or beef. Farmed salmon is slightly cheaper, about 17USD/kg. Salmon is
    very much richer in omega-3 acids than gadoids, fillets anyway, so farmed
    salmon is a much better buy if omega-3 intake is of concern. Pelagic fish,
    herring and mackerel, on a fillet basis, are a little cheaper still, but
    still more expensive than chicken or cheaper cuts of red meat. Official
    health guidelines recommend that we consume one portion a week of fatty
    fish. Assuming a portion is 150g of fillet and a world population of 6
    billion, this would require 100 million tonnes live weight of oily, that is
    predominately pelagic, fish. Total world fishery production of all sorts of
    aquatic animals for all outlets, human consumption and for reduction, is
    around 130 million tonnes, insufficient for all persons in the world to have
    one helping of fatty fish a week even if all the pelagic fish going for
    reduction is diverted to human consumption. Now that is the paradox.

    Peter Howgate

    ----- Original Message -----
    From: "Liz Brown" <bfeab@uaf.edu>
    To: "seafood" <seafood@ucdavis.edu>
    Cc: "Laine Welch" <msfish@alaska.com>; "Bristol BayTimes"
    <bbtimes@nushtel.com>; "Victoria Briggs" <ViedeF97@aol.com>
    Sent: Thursday, March 30, 2006 4:30 PM
    Subject: dissing omega 3

    > Here's the first 'not all it's cracked it up to be' story I've seen about
    > omega 3:
    > http://bmj.bmjjournals.com/cgi/rapidpdf/bmj.38798.680185.47v1?hrss=1
    >
    > Here's a link to the source for the assertion that we should stop eating
    > fish because we've depleted the world's stocks:
    > http://www.nature.com/nature/journal/v423/n6937/full/nature01610.html
    >
    > My knee jerk reaction is that this is irresponsibly ignoring that many
    > fisheries are managed sustainably. I would be interested in hearing other
    > perspectives.
    >
    > --
    > Liz Brown
    > Marine Advisory Program
    > University of Alaska Fairbanks
    > PO Box 1549
    > Dillingham, AK 99576
    > 907-842-1265
    > Fax 907-842-3202
    > www.uaf.edu/map
    >
    >
    >
    >



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