The detection Limit of any analysis cannot be ZERO
this is a physical impossibility.
I would sincerely question the technical expertise of anyone claiming a ZERO
detection limit for an analysis.
cross reactivity is an essentially unrelated parameter of specificity
tests can be highly sensitive [very low detection limits] but have poor
specificity and the converse etc.
Also I have been told by the FDA lab staff in Denver that they are not using
screening tests but are going straight to the GC-ECD method published in
JAOAC by them for all samples - then confirming any positives by GC-MS.
Jerry
Laboratory Director
ANRESCO
-----Original Message-----
From: Gabriel Rivera [mailto:griveralo@yahoo.com]
Sent: Wednesday, February 20, 2002 7:36 AM
To: Daniel_Núñez_T.; seafood@ucdavis.edu
Subject: Re: Chloramphenicol rapid test
Daniel:
Here in Ecuador there are some institutions (SGS, INP,
etc.) which are doing ELISA tests for chloramphenicol.
This is the standard method accepted by FDA as first
method of chloramphenicol detection. If this method
give a postive result, then they check by HPLC to
confirm.
They say the detection limit for ELISA is 0 (zero),
but there is an incidence percentage, 0.01%, for cross
reactions with other antibiotics of the same family
(tiamphenicol and florfenicol).
--- "Daniel_Núñez_T." <daniel@sudamar.com> escribió:
> Dear list members:
>
> Does anyone know the reliability of the rapid tests
> kits for chloramphenicol detection in shrimp
> (aquaculture)?
>
> I found one in internet site of the AOAC:
>
> Chloramphenicol r-Biopharm GmbH / Bio-Tek
> Instruments, Inc. in USA RIDASCREEN Chloramphenicol
> milk, meat, eggs, media
>
>
> Does anyone hear about their results with these kind
> of tests?
>
> Are there more companies that work with these kind
> of tests?
>
> Thanks in advance for your cooperation.
>
> Best regards,
>
> Eng. Daniel Núñez T.
> ASQ Certified Quality Auditor - HACCP Lead Auditor
> Sudamar Technical Manager - Seafood Quality
> Assurance Company
>
>
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