Re: BSE analysis for fish soluble

From: Anthony P. Bimbo (apbimbo@crosslink.net)
Date: Wed Feb 13 2002 - 06:59:04 PST

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    Hi: The following might be helpful to you.

    BSE regulations

    · Additional regulations have been developed to prevent the introduction of
    bovine spongiform encephalopathy (BSE) into the United States. Effective
    October 12, 2001, all processed animal proteins from countries not affected
    by BSE must be accompanied by an original certificate signed by a
    veterinarian of the agency responsible for animal health in the exporting
    region. Shipments not accompanied by the correct documentation are to be
    refused entry into the US as of the October 12 deadline. Brokers/importers
    will be given the option of destroying the shipment or re-exportation. Some
    of the items that will require this certificate include:

    · Meat meal

    · Bone meal

    · Meat and bone meal

    · Blood meal

    · Dried plasma and other blood products

    · Poultry meal

    · Feather meal

    · Offal

    · Tankage

    · Fish meal

    · Fish oil

    This list is not all-inclusive. For questions regarding whether a shipment
    requires this certification, contact Veterinary Services, National Center
    for Import and Export at +1.301.734.3277 or the Plant Protection and
    Quarantine's Veterinary Medical Office at +1.301.734.7633.

    _____________________________

    As far as analysis goes, it is still in the development stage but the
    following might be of interest.

    i) Feed microscopy

    ii) Near infra-red spectroscopy (NIR)

    iii) ELISA

    iv) PCR

    i) Feed Microscopy (UK DEFRA, Luddington)

    A project to detect levels of two types of mammalian meat and bonemeal
    (MMBM), one with high and the other with low bone content, at levels of 2%,
    1%, 0.5% and 0.1% in various background feeds was carried out by the UK
    Government Veterinary Laboratory at Luddington. A trained technician
    succeeded in detecting down to 0.1% of both MMBM materials in fishmeal,
    rapeseed meal and sunflower. However, more time was needed with fish meal,
    (30 minutes per sample), making the method more time consuming than in
    rapeseed meal (2 minutes), and limited by the need for specialist trained
    personnel.

    ii) NIR (Scottish Agricultural College, Aberdeen)

    Using NIR calibrated with 67 samples of contaminated (with MMBM) and
    non-contaminated fishmeal, 69 'blind' samples were tested with 0, 3%, 6% and
    9% MMBM. All contaminated samples were detected, but one pure sample was
    reported as contaminated - a false positive. It is believed this method,
    with further calibration, could detect down to 1%. Because it is so rapid,
    it could be used for widespread screening for fraudulent adulteration -
    likely to be over 3% for fraud to be justified, rather than contamination.

    iii) ELISA (Immunolex/State Serum Institute, Copenhagen

    This test is based on an antibody reaction (antibodies produced in rabbits)
    to different proteins. They cross-react with new sites created on the
    heated (133o, 140o and 156o) proteins from different species, but can be
    made species-specific. Immunolex are confident that the method is already
    very species specific and sensitive even to products subjected to the
    highest temperature (156o). They claim it will detect as little as 0.1%
    MMBM, but require a further six months to fully develop the test. They
    believe it could be developed to allow material to be tested by a 'dip-stick
    ' which changes colour.

    iv) PCR Atlangene Laboratory, France

    This laboratory has developed a method of DNA identification by polymerase
    chain reaction (PCR). They amplify and identify regions of mitochondrial
    DNA that are species-specific. They have been successful with material
    heated to 114oC and are confident the method will work for material heated
    up to 140oC.

    Whilst the above ELISA and PCR tests identify animal meals by species, the
    PCR method would not differentiate milk protein from MMBM. The ELISA method
    needs testing in this respect, but could in theory be adapted either to
    detect or not to detect milk proteins.

    Regards

    Tony Bimbo

    ----- Original Message -----
    From: "Lorena Noriega Orozco" <lnoriega@cascabel.ciad.mx>
    To: <seafood@ucdavis.edu>
    Sent: Tuesday, February 12, 2002 6:33 PM
    Subject: BSE analysis for fish soluble

    > Does any of you know the reason that a BSE analysis is
    > necesary to import fish soluble (to use as fertilizer) to
    > USA, and who can carry out the anlaysis?.
    >
    > Thanks in advance for any help,
    >
    > Lorena Noriega
    > CIAD Unidad Guaymas
    >
    >



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