Whoops! Apologies. I used the 'Reply to al' button, then omitted to copy in
the message i had composed off-line. here it is:
Try the following site:
http://www.pasteur.fr/sante/socpatex/pages/english/97n4sum.html
It is the contents list of an issue of a journal, Bulletin de la Societe de
Pathologie Exotique. 90(4), 286-290. The abstract follows. The text can be
downloaded. It reports that two toxins were isolated and their structures
were being studied.
What is the Yasumoto, 1998, reference?
Peter Howgate
----------------
Seafood poisonings in Madagascar. [complete text under pdf format]
Champetier de Ribes G, Rasolofonirina RN, Ranaivoson G, Razafimahefa N,
Rakotoson JD & Rabeson D
If seafood poisonings are well documented in the Pacific region, they are
not often reported in the Indian Ocean. In Madagascar, fishermen and people
living in coastal areas are traditionally aware of seafood poisonings . Mass
intoxications were described in the sixties, including lethal cases
following sardine ingestion. From 1989 to 1993, 28 ichtyosarcotoxism cases,
mainly ciguatera occurring in children, were reported in Tulear hospital .
>From July 1993 to May 1996, nine seafood poisoning outbreaks occurred in
coastal villages after turtle, shark and sardine meals. Clinical symptoms
were related to marine toxins. For turtle intoxications, gastro-intestinal
symptoms are the most frequently seen (acute stomatitis, dysphagia, vomiting
and diarrhea) , with case fatality rates around 7 %. For shark
intoxications, the most frequent symptoms were neurologic (paresthesia
specially peribuccal and extremities), and gastro-intestinal (diarrhea and
vomiting), with specific case fatality rates varying from 0 % to 30 %. For
sardine intoxication, symptoms were gastro-intestinal (vomiting) and
neurologic (paresthesia), and from the two intoxicated people one died.
Two previously unknown biotoxins were isolated from the liver of a shark
responsible for a mass poisoning, namely carchatoxins. For the turtles, the
search of chelonitoxin is under way. For the sardines, clupeotoxin was
isolated. Because of the frequency and the gravity of collective seafood
poisonings occurring in recent years, the Ministry of Health has implemented
a Seafood Poisoning National Control Programme. This programme is based on
three major strategies : the setting of an epidemiological surveillance
network, the prevention of the communities through educational programmes,
and the developpement of research on marine eco-environment.
----- Original Message -----
From: Richard Lord <fishinfo@guernsey.net>
To: <seafood@ucdavis.edu>
Sent: Tuesday, November 14, 2000 2:58 PM
Subject: FW: Carchatoxins?
> Of interest to this list. Please reply to Marc with copy to me or list.
Thanks.
>
> -----Original Message-----
> From: Marc Baldwin [SMTP:baldwin_marc@altavista.com]
> Sent: 14 November 2000 11:23
> To: ELASMO-L@luc.edu
> Subject: Carchatoxins?
>
> Yasumoto (1998) reports two toxins (Carchatoxins A and B) that were the
probably the cause of an outbreak of food poisoning in Madagascar (in 1993 I
think). However, whilst there is chromatographic data for the toxins there
is no molecular characterisation. Has anyone done any further research on
these or know of any other instances where these Carcharatoxins have been
implicated in poisoning? Any information would be appreciated. Thanks
for your time.
> Marc
>
>
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