Re: YPS saga

From: Robert A. LaBudde (ral@lcfltd.com)
Date: Thu May 04 2000 - 16:40:55 PDT

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    At 11:14 AM 5/4/00 -0700, Paul wrote:
    >Let's say that a reasonable portion of smoked fish is 4 ounces or 114 grams.
    >Let's also say that the salt content of this fish is 3%--probably a bit
    >high, but let's use that figure. Therefore, in that portion, there will be
    >3.42 grams of salt.
    >If 13 ppm of that salt is YPS, then the YPS consumed will be 0.00004446
    >grams.

    Thanks for an intelligent thumbnail sketch of the hazard level involved!

    Some further comments:

    3.42g x 0.001 YPS = 0.00342 g YPS (usually YPS added at 0.1%)

    >Recently Dr. LaBudde stated that the LD50 for Sodium Cyanide (which has a
    >higher level of CN!) was 15 mg. per kg!

    For a 50 kg person, 50 x 15 = 0.750 g NaCN vs 0.001g YPS.

    Also:

    1. Remember the action of cyanide as a toxin is against the heme iron of
    the blood stream. In YPS, the cyanide is ALREADY bound to iron, so this
    would DRAMATICALLY reduce its toxicity.

    2. The dose is effective based on ratio to body weight. As with NaNO2, the
    chance for significant toxicity, if any, would be limited to infants.

    3. The principal dangers of YPS as a PURE COMPOUND are handling dangers
    with respect to acid and heat.

    4. You have to also calibrate the intake danger vs other dietary sources of
    cyanide. Many fruits and vegetables contain some. Including cassava root,
    which is a principal foodstuff of the tropics.

    5. The response of the body to very low grade cyanide poisoning would be to
    very slightly increase red blood cell count to counteract it.

    6. This whole issue is about the word "cyanide" as a bugaboo, rather than
    any measurable risk from YPS use in salt.

    7. The epidemiological experiment needed would be to compare very large
    cohorts of people using and not using YPS-salt, and see if any difference
    in red blood cell count could be found. This would indicate a measurable
    response to the YPS. It would not, however, indicate the importance.
    (Similar effects are obvious in populations living in mountainous areas.)

    ================================================================
    Robert A. LaBudde, PhD, PAS, Dpl. ACAFS e-mail: ral@lcfltd.com
    Least Cost Formulations, Ltd. URL: http://lcfltd.com/
    824 Timberlake Drive Tel: 757-467-0954
    Virginia Beach, VA 23464-3239 Fax: 757-467-2947

    "Vere scire est per causas scire"
    ================================================================



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